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rifabutin will lower the extent or effect of modafinil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.Modafinil excels at what it absolutely was initially intended to do: it promotes wakefulness, improves alertness, and improves mental purpose in a very sleep-deprived state.Serotonin: Modafinil is understood to